導讀： 簡介: 封面內容介紹This volume on Cell Death Proteins is timely in view of the explosiveinterest in programmed cell death or apoptosis, the obvious counterpartto cell proliferation. Although the field is progr 簡介:
封面


內容介紹
This volume on Cell Death Proteins is timely in view of the explosive
interest in programmed cell death or apoptosis, the obvious counterpart
to cell proliferation. Although the field is progressing rapidly, this volume
is a snapshot in time of several topics important to our knowledge
of apoptosis.
Of the six contributions included here, some focus on apoptotic proteins
and others on the inhibitors of apoptosis. The first paper is from
the laboratory of R. Muschel and collaborators, who discourse on cell
cycle checkpoints and apoptosis. M. Tocci reviews the structure and
function of interleukin-1P-converting enzyme, the prototypical protease
involved in the mammalian cell death machine. R. Baserga and
collaborators discuss the role of IGF-I receptor in apoptosis. J. Reed reviews
the Bcl-2 family of proteins, and L. Grasso and W. E. Mercer review
p53-dependent apoptosis. Finally, A. Uren and D. Vaw inform us
about viral inhibitors of apoptosis.
Thus, the contents of this book provide an excellent overview of some
of the major players in the cell death cascade and its controls. Interested
readers will be found in every sector of modern biological research,
including cancer research, signal transduction, and biochemistry.
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